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Exercise Reduces Neuropathic Pain

June 3, 2012

ScienceDaily recently reviewed an interesting study examining the effect of exercise on nerve pain such as that caused by trauma or diabetes. The study suggests that “Exercise helps to alleviate pain related to nerve damage by reducing levels of certain inflammatory factors.”

 

The Gist

Researchers examined the effects of sciatic nerve pain in rats. Post-injury, some rats performed progressive exercise including swimming and walking on a treadmill over several weeks while researchers monitored observable pain behaviors.

The researchers noticed a significant reduction in neuropathic pain in the group that performed exercise post-injury. Those suffering from nerve injuries are known to have abnormal pain responses to changes in pressure or to changes in temperature. The researchers observed that the exercise group did not show abnormal pain responses when they encountered changes to these elements and thus the researchers attributed this to a reduced pain response.

 

The Nitty-Gritty

Previous studies have suggested that inflammation (including pro-inflammatory cytokines) play a significant role in the neuropathic pain response to nerve injury. Researchers found that exercise led to an increased expression of a protein which may have contributed to a reduced expression of the inflammation-promoting cytokines in sciatic nerve tissue.

 

Why We Care

When dealing with nerve pain that cannot be controlled with conventional pain medication, many attempt to regulate nerve pain using antidepressant drugs or others that carry unwanted side effects.

We know that exercise can help reduce pain in people with chronic conditions, so why not also in those with neuropathic pain?

While exercise may not eliminate nerve injury pain, if it can reduce pain up to 50% as demonstrated in this study, this is a significant step in the right direction towards reducing the inflammation in injured nerve tissue.


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